Faculty
The Center for Vectorborne Diseases comprises of 33 collaborators. Three of these collaborators --
Janet Foley,
Aaron Brault and
William Reisen -- have appointments in the Center.
Aaron C. Brault, Ph.D.
Associate Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Associate Arbovirologist, Center for Vectorborne Diseases
Office: 5327 VM3A
Lab: 5336 VM3A Phone: (530) 754-8359
E-mail: acbrault@ucdavis.edu
Aaron Brault's Departmental Profile
Expertise:
- Molecular identification of arthropod infectivity and vertebrate pathogenesis determinants of arthropod-borne viruses
Research Focus:
- West Nile virus (WNV) determinants of avian virulence
- Molecular epidemiology of alpha and flaviviruses
- Adaptive mutations of WNV for increased replication in avian and mosquito hosts
- Development of novel diagnostic assays for arthropod-borne virus detection
Anthony J. Cornel, Ph.D.
Associate Professor, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office and Lab:
Mosquito Control Research Laboratory
UC Kearney Agricultural Center
9240 S. Riverbend Ave.
Parlier, California
93648,
Phone: (559) 646-6556
E-mail: cornel@uckac.edu
Anthony Cornel's Departmental Profile
Expertise:
- Mosquito ecology, genomics, systematics and population genetics
Research Focus:
- Insecticide resistance in West Nile virus and malaria mosquito vectors
- Population structure and systematics of the Culex pipiens complex
- Population structure of the Anopheles gambiae complex
- Vector competency of Culex pipiens complex for West Nile virus
Blaine L. Beaman, Ph.D.
Professor, Department of Medical Microbiology and Immunology
School of Medicine, UC Davis
Office: Room 3228 Tupper Hall
Lab: Room 3213 Tupper Hall
Phone: (530) 752-9663
E-mail: blbeaman@ucdavis.edu
Blaine Beaman's Departmental Profile
Expertise:
- Mechanisms of microbial pathogenesis and host responses
Research Focus:
- Role of Gamma Delta T cells in pulmonary responses with an emphasis on host responses to nocardiae
- Mechanisms of cellular apoptosis
- Mechanisms of bacterial induced neurodegeneration
- Mechanisms of nocardial pathogenesis
Bruce D. Hammock, Ph.D.
Distinguished Professor, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office: 90 Briggs Hall
Labs: Briggs and Everson halls
Phone: (530) 752-7519
E-mail: bdhammock@ucdavis.edu
Bruce Hammock's Web Pages:
Expertise:
- Resistance of mosquitoes to pesticides
Research Focus:
- Identification of enzymes responsible for insecticide resistance
- Correlations of enzyme levels to resistance genes
Bruce F. Eldridge, Ph.D.
Professor Emeritus,
Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office: Center for Vectorborne Diseases, Old Davis Road
Phone: (530) 754-8121
E-mail: bfeldridge@ucdavis.edu
Bruce Eldridge's Web Pages:
Expertise:
- Biology and control of mosquitoes and mosquitoborne human pathogens
Research Focus:
- Mosquitoborne arboviruses
- Factors affecting temporal and spatial distribution of arboviruses
- Long term and short term changes in mosquito faunae
- Development of biological data structures
Bruno Chomel , D.V.M., Ph.D.
Professor, Department of Population Health and Reproduction
School of Veterinary Medicine, UC Davis
Office: 1021 Haring Hall
Lab: 302 Surge IV
Phone: (530) 752-8112
E-mail: bbchomel@ucdavis.edu
Bruno Chomel's Web Pages:
Expertise:
- Epidemiology of zoonotic diseases, emerging zoonotic diseases, veterinary public health
Research Focus:
- Bartonella infections in animals and humans; molecular epidemiology, vectors and wildlife reservoirs
- Serosurveys of zoonotic diseases in wildlife
Dennis W. Wilson, D.V.M., Ph.D.
Professor and Chair, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Office: 1044 Haring Hall
Lab: 2150 Haring Hall
Phone: (530) 752-0158 or 754-8714
E-mail: dwwilson@ucdavis.edu
Dennis Wilson's Web Pages:
Expertise:
- Pulmonary pathology
- Toxicologic pathology
- Environmental cardiology
Research Focus:
- Pulmonary hypertension
- Atherosclerosis
- Cardiovascular effects of environmental particulate matter
Gregory C. Lanzaro, Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Director, UC Malaria Research and Control Group
Office and Lab: Haring Hall
Phone: (530) 752-5652
Lab: (530) 754-8542
E-mail: gclanzaro@ucdavis.edu
Gregory Lanzaro's Web Pages:
Expertise:
- Molecular and population genetics of disease vector
Research Focus:
- Population and molecular genetics of insect vectors of human disease, with an emphasis on malaria in Africa
- Molecular genetics and immunology of insect vector salivary proteins
Holly B. Ernest, D.V.M., Ph.D.
Assistant Professor-in-residence, Department of Population Health and Reproduction
School of Veterinary Medicine, UC Davis
Phone: (530) 752-8245
E-mail: hbernest@ucdavis.edu
Holly Ernest's Web Pages:
Expertise:
- Wildlife population genetics
- Wildlife population health, diseases and disease ecology
- Ecology
of free-ranging raptors, corvids, and carnivorous mammals (bears,
mountain lions, wild pigs and sea otters) with emphasis on California
species
Research Focus:
- Disease ecology, pathology, and impacts of West Nile Virus in yellow-billed magpies
- Population
genetics analysis of West Nile virus impacts to yellow-billed magpies,
American crows, and Western scrub-jays
- Disease ecology
and landscape genetics of California hawks (Swainson’s hawks,
red-tailed hawks, red-shouldered hawks, Coopers hawks, etc) and owls
(great gray owls and spotted owls)
- Landscape genetics
of California terrestrial carnivores (bears, mountain lions and wild
pigs); Familial (kinship/genetic) associations of California sea otters
with diseases
Ian A. Gardner, Ph.D.
Professor, Department of Medicine and Epidemiology
School of Veterinary Medicine, UC Davis
Office: 2415A Tupper Hall
Lab: 1317 Tupper Hall
Phone: (530) 752-6992
E-mail: iagardner@ucdavis.edu
Ian Gardner's Departmental Profile
Expertise:
- Epidemiology, Bayesian modeling, risk analysis
Research Focus:
- Collaborator on epidemiologic aspects of bluetongue and West Nile virus infections with Dr. N. James MacLachlan
Janet E. Foley, D.V.M., Ph.D.
Associate Professor, Department of Medicine and Epidemiology
School of Veterinary Medicine, UC Davis
Research Epidemiologist, Center for Vectorborne Diseases
Office and Lab: 1320 Tupper Hall
Phone: (530) 752-9387
E-mail: jefoley@ucdavis.edu
Expertise:
- Tick- and vector-borne diseases
Research Focus:
- Ecology and pathogenesis of Anaplasma phagocytophilum and Lyme disease
- Rickettsial pathogens of domestic animals and wildlife
- Plague
- Vectorborne disease modeling
Curriculum Vitae
Janet Elizabeth Foley, MS, DVM, Ph.D
Department of Medicine and Epidemiology
School of Veterinary Medicine
University of California
Davis, California 95616
Education:
Doctor of Philosophy, Disease ecology 6/1997, UC Davis Graduate Group in Ecology
Doctor of Veterinary Medicine, 12/1993, UC Davis School of Veterinary Medicine
Master of Science, Population Biology 1987, George Mason University, Fairfax VA
Bachelor of Arts, Philosophy 1985, Honors, George Mason University, Fairfax VA
Work Experience:
2006-present: Associate Professor, Vectorborne Disease Epidemiology, UC Davis Department of Medicine and Epidemiology
2003-2006: Assistant Professor, Vectorborne Disease Epidemiology, UC Davis Department of Medicine and Epidemiology
1/01-2003: Director, Maddie's Shelter Medicine Program, UC Davis
6/01-2003: Assistant Professor, Vectorborne Disease Epidemiology, UC Davis Department of Medicine and Epidemiology
1/01-2003: Director, Maddie's Shelter Medicine Program, UC Davis
6/01-2003: Adjunct Assistant Professor, Medicine and Epidemiology, UC Davis
7/00-7/01: Acting Chief, Microbiology Service, VMTH, UC Davis
7/00-7/01: Lecturer, Microbiology, Dept. of Pathology, Microbiology, and Immunology, UC Davis School of Veterinary Medicine
6/97-7/00: Asst. Research Epidemiologist, Medicine and Epidemiology, UC Davis School of Vet. Med. Ecology of ehrlichiae, small animal infectious diseases.
6/94-10/99: Relief Veterinarian, Sacramento Emergency Veterinary Clinic.
10/94-6/97: Research fellow, Center for Companion Animal Health, UC Davis. Coronaviral ecology, human granulocytic ehrlichiosis, emerging pathogens.
10/96-present: Infectious Disease Consultant, Veterinary Medical Teaching Hospital, UC Davis.
6/94-3/95: Veterinarian, Sacramento Emergency Veterinary Clinic, Sacramento. CA.
1/94-10/94: Veterinarian, Sunset Whitney Veterinary Hospital, Rocklin. CA
2/93-10/94: Scientific aide, California Dept. of Fish and Game
8/87-6/88: Teaching assistant, UC Davis Dept. of Genetics
6/85-8/87: Research assistant, George Mason University Dept. of Biology
Recent and Significant Publications:
-
1996
-
Poland, A., H. Vennema, J. E. Foley, and N. C. Pedersen: Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus. Journal of Clinical Microbiology 34:3180-3184.
-
1997
-
Foley, J. E.,
A. Poland, J. Carlson, and N. C. Pedersen: Patterns of feline
coronavirus infection and fecal shedding from cats in multiple-cat
environments. J Am Vet Med Assoc 210(9):1307-1312.
-
1998
-
Harrus, S., Waner, T. Aizenberg, Z., Foley, J.E.,
Poland, A.M. and Bark, H.: Amplification of ehrlichial DNA from
subclinical cases, 34 months post experimental infection with E. canis. Journal of Clinical Microbiology 36:73-76.
-
Foley, J., Barlough, J., Kimsey, R., Madigan, J.E., DeRock, E. and Poland, A.: Ehrlichia spp. In cervids from California. Journal of Wildlife Diseases 34:731-737.
-
Foley, J.,
Harrus, S., Poland, A., Chomel, B. and Pedersen, N.C.: Molecular,
clinical, and pathological comparison of two distinct strains of Hemobartonella felis in domestic cats. American Journal of Veterinary Research 59:1581-1588.
-
1999
-
Foley, J.,
Lerche, N., Dumler, J, Madigan, J.E.: A simian model of human
granulocytic ehrlichiosis. American Journal of Tropical Medicine and
Hygiene 60:987-93.
-
Foley, J., Foley, P., Pedersen, N.: The persistence of an SIS disease in a metapopulation. Journal of Applied Ecology 36:555-563.
-
Foley, J.E.,
Crawford-Miksza, L., Dumler, J.: Two cases of human granulocytic
ehrlichiosis in northern California. Clinical Infectious Disease
29:388-392.
-
Foley, J.E., Foley, P., Jecker, M.: Infection with granulocytic ehrlichia and infestation with the tick vector, Ixodes pacificus, in California mountain lions (Puma concolor). Journal of Wildlife Diseases 35:703-709.
-
2000
-
Chae, J-S, Foley, J.E.,
Dumler, JS, Madigan, JE. Comparison of the nucleotide sequences of
16SrRNA, 444 Ep-ank, and groESL heat shock operon genes in naturally
occurring Ehrlichia equi and human granulocytic ehrlichiosis agent isolates from northern California. Journal of Clinical Microbiology 38:1364-9.
-
Foley, J.E.
Human ehrlichiosis: a review of clinical disease and epidemiology for
the physician. Infectious Disease in Clinical Practice 9:93-98.
-
Foley JE, Pedersen NC. "Candidatus Mycoplasma hemominutum, a low-virulence epi-erythrocytic parasite of cats. International Journal of Systematic and Evolutionary Bacteriology.
-
Foley J.,
Foley P, Carpenter T. The distribution of granulocytic ehrlichia
seroreactive horses and dogs in California. American Journal of
Veterinary Research 62:1599-1605.
-
2001
-
Lane, R., J. Foley, L.
Eisen, and E. Lennette. Acarologic risk of exposure to emerging
tickborne bacterial pathogens in a semi-rural community in Northern
California. Journal of Vector-borne and Zoonotic Disease 1:197-210.
-
2002
-
Foley J., Kramer V, Weber D, et al. Experimental ehrlichiosis in dusky-footed woodrats (Neotoma fuscipes). Journal of Wildlife Diseases 38:194-198.
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Foley J., Kramer V, Weber D, et al. Experimental ehrlichiosis in dusky-footed woodrats (Neotoma fuscipes). Journal of Wildlife Diseases 38:194-198.
-
Weber, D., K. Danielson, S. Wright, and J. Foley. Hematology and serum biochemistry values of dusky-footed wood rat, (Neotoma fuscipes). Journal of Wildlife Disease 38:194-198.
-
2003
-
Foley J.,
Leutenneger C, Dumler J, et al. FIV-infection and AIDS modulate the
severity of human granulocytic ehrlichiosis in a cat model. Comparative
Immunology, Microbiology, and Infectious Diseases 26:103-113.
-
2004
-
Foley J.E.,
P Foley, RN Brown, RS Lane, JS Dumler and JE Madigan. Ecology of
granulocytic ehrlichiosis and Lyme disease in the western United
States. Journal of Vector Ecology 29(1):41-50.
-
2005
-
Foley, J., E Queen, B Sacks, and P Foley. GIS-facilitated spatial epidemiology of tickborne diseases in coyotes (Canis latrans) in northern and coastal California. CIMID 28:197-212.
-
Teglas, M., R. Matern, S. Lein, P. Foley, S. M. Mahan, and J. Foley. Ticks and tickborne diseases in Guatemalan cattle and horses. Veterinary Parasitology 131: 119-127.
- Sokolow S, C Rand, SL Marks, NL Drazenovich, EJ Kather, and J Foley . Epidemiologic evaluation of diarrhea in dogs in an animal shelter. AJVR 6:1018-1024.
- 2006
- Adjemian, JC, EH Girvetz, Beckett L and JE Foley. Analysis of Genetic Algorithm for Rule-Set Production (GARP) modeling approach for predicting distributions of fleas implicated as vectors of plague, Yersinia pestis, in California. J Med Entomology 43:93-103.
- Drazenovich NL, RN Brown, and JE Foley . Use of real-time quantitative PCR targeting the msp2 protein gene to identify cryptic Anaplasma phagocytophilum infections in wildlife and domestic animals. Vector Borne and Zoonotic Disease 6:83-90.
- Teglas M, and JE Foley. Differences in the transmissibility of two Anaplasma phagocytophilum strains by the North American tick vector species, Ixodes pacificus and Ixodes scapularis (Acari:Ixodidae). Experimental and Applied Acarology 38:47-58.
- Teglas, MB, NL Drazenovich, J Stott, and JE Foley . The geographic distribution of the putative agent of epizootic bovine abortion in the tick vector, Ornithodoros coriaceus. Vet Parasitology 140:327-333.
- Cao WC, Zhan L, He J, Foley JE, DE Vlas SJ, Wu XM, Yang H, Richardus JH, Habbema JD. Natural Anaplasma phagocytophilum infection of ticks and rodents from a forest area of Jilin Province, China. Am J Trop Med Hyg. 75:664-668.
- Barbet AF, Lundgren AM, Alleman AR, Stuen S, Bjöersdorff A, Brown RN, Drazenovich NL, Foley JE. Structure of the expression site reveals global diversity in MSP2/P44 variants of Anaplasma phagocytophilum. Infection and Immunity 74:6429-6437.
-
2007
- Foley J, NC Nieto. Anaplasma phagocytophilum subverts tick salivary gland proteins. Trends in Parasitology 23:3-5.
-
Adjemian J, P Foley, K Gage, and J Foley . 2007. Initiation and spread of traveling waves of plague, Yersinia pestis, in the western United States. American Journal of Tropical Medicine and Hygiene 76:365-375.
-
Foley J, N Drazenovich, C Leutenegger, and B Chomel. Polyarthritis and thrombocytopenia are associated with increased prevalence of vector-borne diseases in California dogs. Vet. Record 160:159-162
-
Nieto NC, Dabritz H, Foley P, Drazenovich N, Calder L, Adjemian J, Conrad PA, Foley JE. Ectoparasite diversity and exposure to vector-borne disease agents in wild rodents in central coastal California. J Med Entomology 44:328-335.
-
Stoddard RA, Miller WG, Foley JE, Lawrence J, Gulland FM, Conrad PA, Byrne BA. Campylobacter insulaenigrae isolates from northern elephant seals (Mirounga angustirostris) in California. Appl Environ Microbiol. 73:1729-1735.
-
Strik N, AR Alleman, AF Barbet, HL Sorenson, HL Wamsley, FP Gaschen, N Luckschander, S Wong, F Chu, JE Foley , A. Bjoersdorff, S Stuen, DP Knowles. 2007. Characterization of Anaplasma phagocytophilum major surface protein 5 and the extent of its cross-reactivity with A. marginale. Clinical and Vaccine Immunology 14:262-268
-
Foley, JE, Zipser, J, Chomael B, Girvetz, E and Foley, P. 2007. Modeling plague persistence in host-vector communities in California. Journal of Wildlife Diseases 43: 408-424.
-
Henn JB, Gabriel MW, Kasten RW, Brown N, Theis JH, Foley JE, Chomel BB. Gray foxes (Urocyon cinereoargenteus) as a potential reservoir of a Bartonella clarridgeiae-like bacterium and domestic dogs as part of a sentinel system for surveillance of zoonotic arthropod-borne pathogens in northern California. J Clin Microbiol. 45:2411-2418.
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Foley J, R Brown, M Gabriel, J Henn, N Drazenovich, R Kasten, S Green, and B Chomel. Spatial epidemiological analysis of tick-borne pathogen exposure in dogs in rural northern California coastal communities. Veterinary Record 19: 653-657
-
Foley J, N Nieto, S Clueit, P Foley, WL Nicholson, and R Brown. Exposure to zoonotic rickettsial pathogens in northern flying squirrels, Glaucomys sabrinus, in northern California. Journal of Wildlife Diseases 43: 684-689.
-
Nieto, N., M. A. Camann, J. Foley, and J. O. Reiss. Disease prevalence and severity associated with integumentary and cloacal parasites in Northern red-legged frog (Rana aurora aurora) tadpoles. Diseases of Aquatic Organisms 78: 61-71.
-
2008
- Foley, J., S. Clueit, and R. N. Brown. Differential exposure to Anaplasma phagocytophilum in rodent species in northern California. Vector Borne and Zoonotic Disease 8: 49-55.
- Foley, J., N. Nieto, J. Adjemian, H. Dabritz, and R. Brown. Anaplasma phagocytophilum infection in small mammal hosts of Ixodes spp. ticks in the western US Emerging Infectious Diseases Epub.
-
Plowright, R., S. Sokolow, J. Foley, and P. Dasczak. Causal inference in disease ecology: investigating ecological drivers of disease emergence. Frontiers in Ecology and the Environment.
-
Plowright, R., H. Field, C. Smith, A. Divljan, C. Palmer, G. Tabor, P. Daszak, and J. Foley. Reproduction and nutritional stress are risk factors for Hendra virus infection in little red flying foxes (Pteropus scapulatus). Proceedings of the Royal Society Biological Sciences Series B epub.
-
In Press
- Foley, J., N. C. Nieto, P. Foley, and M. Teglas. In press-a. Co-phylogenetic analysis of Anaplasma phagocytophilum and its vectors, Ixodes spp. ticks. Experimental and Applied Acarology.
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Foley, J., N. C. Nieto, J. E. Madigan, and J. Sykes. In press-b. Anaplasma phagocytophilum strains in the western US may comprise a genospecies group. Annals of the New York Academy of Science.
-
Hoar, B., N. C. Nieto, A. F. Barbet, D. Rhodes, and J. Foley. In press. Sequential coinfection with Anaplasma phagocytophilum and Anaplasma marginale in cattle. American Journal of Veterinary Research.
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Nieto, N., and J. Foley. In press-a. Meta-analysis of coinfection with Borrelia burgdorferi and Anaplasma phagocytophilum in humans, domestic animals, wildlife, and Ixodes ricinus-complex ticks. Vector Borne and Zoonotic Disease.
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Nieto, N. C., and J. Foley. In press-b. Evaluation of squirrels as ecologically significant hosts for Anaplasma phagocytophilum in California. Journal of Medical Entomology.
Personal Biography

I study the ecology and epidemiology of infectious
diseases in animal and human populations. I have a Ph.D in the ecology
of infectious diseases (UC Davis, 1995) and a DVM, emphasizing ecology and medicine
of wildlife, laboratory animals, and small animals. My veterinary
practice experience includes small animal medicine, emergency medicine,
and working with free-ranging wildlife.
Current Research Interests:
-
Epidemiology of vector-borne diseases (in people, dogs, cats, horses,
and wildlife) in California. Special interests include granulocytic anaplasmosis, Lyme disease, and plague.
- Simulation and
analytical modeling of infectious disease persistence and emergence in
nature, using different pathogen-host systems.
- Infectious diseases in wild carnivores and small mammals.
- Ticks and tick biology
Other:
I
have 2 children, 4 cats, 1 dog, 2 chickens and 2 turtles. My husband,
Patrick Foley, is a theoretical population biologist specializing in
extinction at California State University, Sacramento.
Vectorborne Diseases and Infectious Disease Ecology Laboratory
Our laboratory studies the ecology and epidemiology of
infectious diseases in animal and human populations. We are
particularly interested in the epidemiology of vector-borne diseases, emerging infectious
diseases in wildlife, infectious diseases in feline populations, and
the theory and mathematical modeling of vector-borne diseases in
communities. Much of our work is in rodents and domestic animals and/or
vectored by ticks. Special interests include international veterinary
medicine and ecological research (Asia, Australia, and Mexico),
granulocytic anaplasmosis, Lyme disease, and plague.
Post-doctoral scholars and Graduate Students
Tick Diseases:
We have several research projects focused on the ecology and
epidemiology of ticks and tickborne diseases of California and
elsewhere.
-
Forest change and the emergence of disease transmitted by Ixodes
ricinus group hard ticks in northern California and northeastern China.
- Modeling the enzootic maintenance of granulocytic anaplasmosis in California wildlife.
- Understanding
high anaplasmosis and Lyme- risk regions of far northern California
through wildlife and tick studies.
- Comparative habitat analysis for hard-tick borne disease in the western US.
- Developing an active surveillance program for exotic ticks of cattle in California.
Plague:
Foley Laboratory Graduate Students and Post-docs
In revision
Under construction
Jennifer Gorman
Under construction
Katryna Fleer
Under construction
Nathan Nieto
Nathan Christopher Nieto with squirrel
Nate
is a post-doc working on disease ecology and evolution in the granulocytic anaplasmosis, relapsing fever, and plague systems. Nate graduated from Humboldt State University with a B.S. in Wildlife and
M.A. in Biological Sciences. His Master’s degree focused on the ecology
of an emerging pathogen of amphibians, Batrachochytrium dendrobatidis,
in northern red-legged frogs. During his PhD, Nate elucidated reservoir capacities for multiple contributors to the ecology of granulocytic anaplasmosis, combining field work, animal models, disease pathogenesis, and phylogenetics. Overall, Nate has worked for private, non-profit,
government, and academic institutions as a wildlife biologist and
scientist. Nate's research incorporates
experiments with animal models and field research to better understand
host-pathogen relationships and how this affects disease risk. Some of his favorite activities are mountaineering, surfing, and mountain biking.
Research Interests:
- Ecology of granulocytic anaplasmosis in California (Dissertation research).
- Pathogenesis of rickettsial organisms in animal models.
- Community structure and the ecological maintenance of disease.
- Using phylogeny to explain pathogen evolution.
- General parasitology and the biology of disease vectors.
- Wildlife and conservation biology.
Email: ncnieto@ucdavis.edu
Phone: (530) 754-9740
Sophia Papageorgiou
Research Interests:
Three
potentially devastating tick-borne diseases (Lyme disease- LD;
tick-borne encephalitis- TBE; and granulocytic anaplasmosis- GA) have
emerged in the past two decades in some of the poorest, underdeveloped
regions globally. One economically marginal region suffering the impact
of emerging tick-borne disease is the Inner Mongolia province of China,
an autonomous region along the country’s northern border, adjacent to
Mongolia. In this Chinese province, human LD and GA infections have
been documented and ticks carrying the infections have been identified.
Recently, coinfections with GA and LD have been discovered in northern
China. The reservoir mammalian hosts and transmission mechanisms for
these diseases need to be determined in order to provide
recommendations for surveillance and public health programs.
Inner Mongolia has a population of 24 million people. The economy in
this region is based on the industries of forestry and agriculture,
coal, iron, and steel. Recently there has been extensive degradation of
old-growth forests through over-harvesting, which probably contributed
to the recent emergence of tick-borne diseases. These changes may
initiate a cascade of events ultimately resulting in the emergence of
disease-transmitting arthropods (e.g. ticks) and infectiousdiseases.
Thespecific question we are interested in addressing is how forest
changes affect the ecology of, and health of local communities due to
emerging LD, GA, and TBE near Chao-Er in Inner Mongolia. The question
will be evaluated by measuring disease risk in degraded and undegraded
forests through quantitative measurements on forest richness, tick
density, reservoir host, and determining tick-borne disease diversity
and prevalence in reservoir, vector, and livestock species.
Email: spapageorgiou@ucdavis.edu
Students who graduated and left
Mike Teglas
Raina Plowright
Jennifer Adjemian
Susanna Sokolow
John E. Madigan , D.V.M., MS
Professor, Department of Medicine and Epidemiology
School of Veterinary Medicine, UC Davis
Office: 3105 Tupper Hall
Lab: 3110 Tupper Hall
Phone: (530) 752-6513
E-mail: jemadigan@ucdavis.edu
John Madigan's Departmental Profile
Expertise:
- Vectorborne diseases of horses: Anaplasma phagocytophilum and Neorickettsia risticii
Research Focus:
- Pathogenesis of Anaplasma phagocytophilum
- Life cycle and pathogenesis of Neorickettsia risticii
Kathryn DeRiemer, Ph.D., MPH
Assistant Professor, Department of Public Health Sciences
School of Medicine, UC Davis
1616 Da Vinci Court, Room 1028
Genome and Biological Sciences Facility 5409 (Biosafety Level (BSL) 3 facilty
Phone: (530) 754-5989
E-mail: kderiemer@ucdavis.edu
Kathryn DeRiemer's Departmental Profile
Expertise:
- Molecular epidemiology of Mycobacterium tuberculosis
Research Focus:
- Population-based epidemiologic assessments of transmission, infection and disease
- Strain-specific characteristics of M. tuberculosis
- Host immune response to infection with mycobacteria
- Transmission of airborne infections
Lynn S. Kimsey, Ph.D.
Professor, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Director, Bohart Museum of Entomology
Office: 1124 Academic Surge
Lab: 1124 Academic Surge
Phone: (530) 752-5373
E-mail: lskimsey@ucdavis.edu
Lynn Kimsey's Departmental Profile
Expertise:
- Systematics and biodiversity of California insects
- Urban and suburban pests
- Forensically important insects
Research Focus:
- Insect phylogenetics
- California insect fauna
N. James MacLachlan, D.V.M., Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Office and lab: 1112 Haring
Phone: (530) 754-8124
E-mail: njmaclachlan@ucdavis.edu
James MacLachlan's Departmental Profile
Expertise:
- Pathology and viral pathogenesis
Research Focus:
- Pathogenesis and molecular epidemiology of bluetongue and African horse sickness
- Molecular
characterization of bluetongue and African horse sickness viruses to
develop improved diagnostics and vaccines
- Pathogenesis of Rift Valley fever
Patricia Ann Conrad, D.V.M., Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Office: 2113 Haring Hall
Labs: 2111, 2126 and 1139 Haring Hall
Phone: (530) 752-7210
E-mail: paconrad@ucdavis.edu
Patricia Conrad's Departmental Profile
Expertise:
- Characterization
and ecology of pathogenic protozoal parasites transmitted between
humans, wildlife and domestic animals
Research Focus:
- Molecular biology, immunology and characterization of pathogenic protozoa
- Immunopathogenesis and ecology/epidemiology of zoonotic protozoal parasites
- Primary
focus on the characterization of tick-transmitted hemoprotozoal
parasites and neurotrophic coccidial parasites
- Development
of quantitative molecular assays and assessment of bioindicators for
evaluating sources of fecal pollution in fresh water and marine
ecosystems
Robert K. Washino, Ph.D.
Professor Emeritus and former Chair, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office address: 367C Briggs
Phone: (530) 752-0492
E-mail: rkwashino@ucdavis.edu
Robert Washino's Departmental Profile
Expertise:
- Mosquito biology and control
Research Focus:
- Mosquito biology and control
Satya Dandekar, Ph.D.
Professor and Chair, Department of Medical Microbiology and Immunology
School of Medicine, UC Davis
Office: Department of Medical Microbiology and Immunology
Tupper Hall, Room 3146
Lab: Genome and Biomedical Sciences Building
Room 5511
Phone: (530) 752-3409
E-mail: sdandekar@ucdavis.edu
Satya Dandekar's Departmental Profile
Expertise:
- Infectious diseases and mucosal immunity, HIV research
Research Focus:
- HIV pathogenesis and mucosal immunity and animal models
- Genomic and immunologic aspects of Mucosal innate and adaptive defenses against pathogens
- HIV and associated co-infections and global health with specific emphasis in India
Sharon P. Lawler, Ph.D.
Associate Professor, Department of Entomology
College of Agriculture and Environmental Sciences, UC Davis
Office and Lab: 394 Briggs Hall
Phone: (530) 754-8341
E-mail: splawler@ucdavis.edu
Sharon Lawler's Departmental Profile
Expertise:
- Aquatic community ecology
Research Focus:
- Non-target effects of mosquito control
- Riceland mosquitoes
Shirley Luckhart, Ph.D.
Associate Professor, Department of Medical Microbiology and Immunology
School of Medicine, UC Davis
Office: 3437 Tupper Hall
Lab: 3433, 3456, 3439, 3480 Tupper Hall
Phone: (530) 754-6963
E-mail: sluckhart@ucdavis.edu
Shirley Luckhart's Departmental Profile
Expertise:
- Molecular cell biology of mosquito innate immunity to malaria parasite infection
Research Focus:
- Identification of parasite factors that induce mosquito immune responses
- Identification of regulatory factors and signaling pathways of mosquito innate immune responses
- Cross-talk between mosquito and mammalian immune molecules and growth factors at the interface of bloodfeeding
Stephen W. Barthold, D.V.M., Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Director, Center for Comparative Medicine
Office: Room 2001, Center for Comparative Medicine
Lab: Rooms 1021 and 1027, Center for Comparative Medicine
Phone: (530) 752-1245
E-mail: swbarthold@ucdavis.edu
Stephen Barthold's Web Pages:
Expertise:
- Veterinary
pathologist with 35 years of experience in experimental pathology of
infectious diseases, with emphasis on mouse models
Research Focus:
- Host-agent iinteraction and pathogenesis of Lyme borreliosi
- Host-agent interaction and pathogenesis of granulocytic anaplasmosis
- Host response to Bartonella henselae, the agent of cat scratch disease
Thomas J. Zavortink, Ph.D.
Research Associate, Bohart Museum of Entomology
Affiliate, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office: 1124 Academic Surge
Lab: 1124 Academic Surge
Phone: (530) 752-0492
E-mail: tjzavortink@ucdavis.edu
Thomas Zavortink's Departmental Profile
Expertise:
Research Focus:
- Revision of Puerto Rican Wyeomyia
- Revision of Neotropical genera Runchomyia, Shannoniana, Trichoprosopon
- Revision of Ethiopian subgenus Neomelaniconion of Aedes
- Mosquitoes surveys of Costa Rica, Nicaragua
Thomas W. Scott, Ph.D.
Professor, Department of Entomology
College of Agriculture and Environmental Sciences, UC Davis
Director, Mosquito Research Laboratory
Office: 49 Briggs
Lab: 38 and 55 Briggs
Phone: (530) 754-4196
E-mail: twscott@ucdavis.edu
Thomas Scott's Departmental Profile
Expertise:
- The ecology, epidemiology, and control of vector-borne diseases – emphasis on dengue
Research Focus:
- Epidemiology and prevention mosquito-borne disease
- Heterogeneities in mosquito-borne disease transmission
- Mosquito ecology and the role of mosquitoes in pathogen transmission
Walter M. Boyce, D.V.M., Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Co-Director, Wildlife Health Center
Office: Wildlife Health Center, TB 128
Lab: 2105 Haring Hall
Phone: (530) 752-1401
E-mail: wmboyce@ucdavis.edu
Walter Boyce's Departmental Profile
Expertise:
- Veterinary parasitology and immunoparasitology; wildlife disease and ecology
Research Focus:
- Wildlife health and conservation and management of wildlife
- The ecology and epidemiology of disease at wildlife interface
- Zoonotic diseases, including West Nile virus and avian influenza
- Parasitism and predation in wildlife populations
Walter S. Leal, Ph.D.
Professor and Chair, Department of Entomology
College of Agricultural and Environmental Sciences, UC Davis
Office and Lab: 37 Briggs Hall
Phone: (530) 752-7755
E-mail: wsleal@ucdavis.edu
Walter Leal's Departmental Profile
Walter Leal's Research
Expertise:
- Molecular basis of olfaction
Research Focus:
- Molecular basis of mosquito olfaction, with particular emphasis on odorant binding, release, and inactivation
- Chemical ecology- and sensory physiology-based approaches aimed at the discovery of novel attractants
William K. Reisen, Ph.D.
Professor, Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine, UC Davis
Research Entomologist, Center for Vectorborne Diseases
Office: Center for Vectorborne Diseases, Old Davis Road, Davis, CA 95616
Phone: (530) 752-0124
E-mail:
wkreisen@ucdavis.edu
Expertise:
- Ecology and control of arboviruses and their vertebrate and arthropod hosts in California
Research Focus:
- Mosquito vector competence and vectorial capacity in relation to arbovirus transmission
- Avian seroprevalence and host competence for arboviruses
- Arbovirus surveillance diagnostics and data management
- Mosquito and arbovirus control
Biography and Curriculum Vitae
Research entomologist William K. Reisen is a full-time faculty member with
the UC Davis Center for Vectorborne Diseases (CVEC) and an adjunct professor in
the Department of Pathology,
Microbiology and Immunology, School of Veterinary Medicine, UC Davis.
At CVEC, Dr. Reisen directs the Arbovirus Research Program and participates in the Environmental Assessment and Information Technology Program (EAIT).
Expertise: Mosquito and vectorborne
disease ecology
Research focus: Population ecology of
mosquitoes and their vertebrate hosts in relation to the epidemiology,
surveillance and control of mosquito-borne pathogens
Grants: He receives grants from the National Institutes of
Health, National Oceanographic and Atmospheric Administration, Centers for
Disease Control and Prevention, NASA, and the UC Mosquito Research Program, and
support from the Coachella Valley, Greater Los Angeles County, Kern, and
Sacramento-Yolo Mosquito and Vector Control Districts (MVCD).
Contact Information:
E-mail: wkreisen@ucdavis.edu
Office:
CVEC, Old Davis Road, One Shields Ave., Davis, CA 95616
Phone: (530)
752-0124
Fax: (530) 754-6360
Education:
- B.S. in agriculture (entomology - plant pathology), University of Delaware,
Newark
- M.S. in zoology from Clemson University, Clemson, S. C. His supporting
field: Experimental Statistics. His thesis: “Some ecological relationships of
the organic drift in Prater’s Creek, Pickens County, South Carolina.”
- Ph.D. in zoology from the University of Oklahoma, Norman, Okla. Supporting
fields: medical microbiology, ecology. Dissertation: “The ecology of larval
black flies (Diptera: Simuliidae) in a south central Oklahoma stream.” Areas of
academic concentration: entomology, plant and animal ecology, microbiology
including plant pathology, experimental statistics (including computer science),
and chemistry.
Professional
Experience:
1967-1968: Research assistant, Clemson University; Duties:
Monitoring organochloride insecticide residues in fish and aquatic insects.
1968: Teaching Assistant, Clemson University; Course taught:
Animal Ecology; Research: Stream ecology and fish feeding behavior.
1969-1971: Captain, U.S. Air Force; Assignments:
Epidemiological Laboratory, Lackland AFB, Texas, and 5 th Epidemiological
Flight, Manila and 1st Medical Service Wing, Clark AB, Republic of the
Philippines; Duties: Vector-borne disease surveillance and control programs on
USAF Bases in Pacific Air Command. Temporary duty in Japan, Taiwan, Korea,
Okinawa, Thailand, Guam and Hawaii.
1971-1974: Teaching Assistant, University of Oklahoma,
Norman. Courses taught: Introductory Zoology, Invertebrate Zoology, Entomology,
Ecology, and Parasitology; Research: Simuliid demography, stream ecology, rodent
and bat ectoparasites.
1974-1975: Research Associate, University of Maryland School
of Medicine, Baltimore; Research: Blood feeding behavior and larval
intraspecific competition in Anopheles stephensi.
1975-1980: Assistant Professor of International Medicine at
the Pakistan Medical Research Centre, University of Maryland School of Medicine,
Lahore, Pakistan; Research: Population ecology and bionomics of Pakistan
mosquitoes and their relation to pathogen transmission; experimentation towards
the application of genetical systems for mosquito control.
1980-1995: Research Entomologist and Director, Arbovirus
Field Station, School of Public Health, University of California, Berkeley;
Research: Population ecology, bionomics, genetics and vector competence of
Culex tarsalis in relation to arbovirus ecology and control in
California.
1995-present: Research Entomologist, Director, Arbovirus
Field Station, Center for Vectoborne Disease Research, Adjunct Professor,
Department of Pathology, Microbiology and Immunology, School of Veterinary
Medicine, University of California, Davis; Research: Population ecology of
Culex tarsalis and other mosquitoes and their vertebrate hosts in
relation to the epidemiology, surveillance and control of arboviruses.
Professional Activities:
-
Society Memberships
- American Mosquito Control Association
- Mosquito and Vector Control Association of California
- Entomological Society of America, Society for Vector Ecology
- American Society of Tropical Medicine and Hygiene
-
Offices held in Societies
- 1988 - present: Co-editor or Subject Editor, Journal of Medical Entomology, Entomological Society of America
- 1989 - 1992: Vice President, President-elect and President, Society for Vector Ecology
- 1989 - 1994: American Committee on Medical Entomology, American Society of Tropical Medicine and Hygiene
- 1990 - 2001: Chairman, Disease Control Subcommittee, California Mosquito and Vector Control Association
- 1994 - 1998: Member, Exotic Genome Committee, American Mosquito Control Association
- 1994 - present: Member and Chair, Vector Control Advisory Committee, California Department of Public Health
- 1996 - 1998: Secretary, Chairman elect and Chairman, Section D, Entomological Society of America
- 1999: Member, Awards Committee, Society for Vector Ecology
- 1999 - 2004: Chairman, Editorial Board, Journal of the American Mosquito Control Association
- 2000 - present: Assistant Editor, Vector-borne and Zoonotic Diseases
- 2000 - present: Member, West Nile working group, California Department of Public Health
- 2001 - 2002: Chair, Nominations Committee, Society for Vector Ecology
- 2001 - 2005: Member, West Nile Task Force, Kern County
- 2001 - present: Chairman, Vector and Vector-borne Disease Committee, Mosquito and Vector Control Association of California
- 2004: Chair, Publications Council, Entomological Society of America
- 2004: Member, Nomination committee, Society for Vector Ecology
- 2005: Member, Reeves’ Student award committee, Mosquito and Vector Control Association of California
-
Honors
- Arthur T. Bragg Award for outstanding research in natural history, University of Oklahoma, 1974
- Lifetime Award for Achievement in Medical Entomology, Society for Vector Ecology, 2001
- Fellow, Entomological Society of America, 2003
- Academic Federation Award for Excellence in Research, University of California, Davis, 2004
- John N. Belkin Award for excellence in Vector Ecology, American Mosquito Control Association, 2006
Publications:
-
2006
- Reisen, WK, Y Fang and VM Martinez. Vector competence of Culiseta incidens and Culex thriambus for West Nile Virus. J. Amer. Mosq. Control. Assoc. [in review]
- Fang, Y and WK Reisen. Previous infection West Nile or St Louis encephalitis viruses provides cross protection during reinfection in House finches. Am. J. Trop. Med. Hyg. [in press]
- Mahmood, M., RE Chiles, Y Fang, EN Green and WK Reisen. Dose, age and genotype effect Culex tarsalis [Diptera: Culicidae] vector competence for Western equine encephalomyelitis virus. J. Amer. Mosq. Control Assoc. [in press]
- Reisen, WK, VM Martinez, Y Fang, S Garcia, S Ashtari, SS. Wheeler and BD Carroll. Role of California (Callipepla californica) and Gambel's
(Callipepla gambelii) quail in the epidemiology of western equine encephalomyelitis, St. Louis encephalitis and West Nile viruses in California, Vector-borne and Zoonotic Dis. [in press]
- Reisen, WK, CM Barker, R Carney, HD Lothrop, SS Wheeler, JL Wilson, MB Madon, R Takahashi, B Carroll, S Garcia, T Fang, M Shafii, S Ashtari, V Kramer, C Glaser, and Jean. Role of Corvids in the epidemiology of West Nile virus in Southern California. J. Med. Entomol. 43: 356-367
- Reisen, WK, Y Fang, H Lothrop, V Martinez, J Wilson, P O'Connor, R Carney, B Cahoon-Young, M Shafii and AC Brault. Overwintering of West Nile virus in southern California. J. Med. Entomol. 43: 344-355.
- Reisen, WK, Y Fang, and VM Martinez. Effects of temperature on the transmission of West Nile virus by Culex tarsalis (Diptera: Culicidae). J. Med. Entomol. 43: 309-317
-
2005
- Hull, J., A. Hull, WK Reisen, Y Fang, H Ernest. Variation in West Nile Virus Antibody Prevalence of Migrating and Wintering Hawks in Central California. Condor
- Trevejo, RT, WK Reisen, G Yoshimura and WC Reeves. Detection of chicken antibodies to mosquito salivary gland antigens by enzyme immunoassay. J. Am. Mosq. Contr. Assoc. 21: 39-48.
- Reisen, WK, SS Wheeler, S Yamamoto, Y Fang and S Garcia. Nesting ardeid colonies are not a focus of elevated West Nile virus activity in Southern California. Vector-borne Zoonotic Dis. 5: 258-266.
- Reisen, WK, Y. Fang, and V.M. Martinez. Avian host and mosquito (Diptera: Culicidae) vector competence determine the efficiency of West Nile and St. Louis encephalitis virus transmission. J. Med. Entomol. 42: 367-375.
- Mahmood F, WK Reisen, RE Chiles and Y Fang. Western equine encephalomyelitis virus infection affects the life table characteristics of Culex tarsalis (Diptera: Culicidae). J. Med. Entomol. 41: 982-985.
-
2004
- Reisen,W., H Lothrop, R Chiles, M Madon, C Cossen, L Woods, S Husted, V Kramer, J Edman. Invasion of California by West Nile Virus. Emerg. Inf. Dis. 10: 1369 - 1378.
- Mahmood,F., RE Chiles, Y Fang, CM Barker and WK Reisen. Role of nestling mourning doves and house finches as amplifying hosts of St. Louis encephalitis virus. J. Med. Entomol. 41: 965-972.
- Reisen WK, Chiles RE, Martinez VM, Green EN, Fang Y. Encephalitis virus persistence in California birds: experimental infections in mourning doves
(Zenaidura macroura). Med Entomol 41: 462-466.
- Reisen WK, Chiles RE, Martinez VM, Y Fang, E Green, S Clark. Effect of dose on house finch infection with Western equine encephalomyelitis and St. Louis encephalitis viruses. J Med Entomol. 41: 978-981
- Mahmood F, Fang Y, Green EN, Clark S, Reisen WK. Evaluation of methods for studying the vector competence of Culex tarsalis for western equine encephalomyelitis virus. J Am Mosq Control Assoc 20: 277-282.
- Chiles RE, Green EN, Fang Y, Goddard L, Roth A, Reisen WK, Scott TW. Blinded laboratory comparison of in situ enzyme immunoassay, the VecTest wicking assay and a reverse transcription-polymeras chain reaction assay to detect mosquitoes infected with West Nile and St. Louis encephalitis viruses. J Med Entomol 41: 539-544.
- Nelson, DM, IA Gardner, RE Chiles, UB Balasuriya, BF Eldridge, TW Scott, WK Reisen and NJ Maclachan. Prevalence of antibodies against Saint Louis encephalitis and Jamestown Canyon viruses in California horses. Comp. Immunol. Microbiol. Inf. Dis. 27: 209-215.